Melatonin is supplied as a catalogued research material in 10 mg.
Melatonin is the small molecule N-acetyl-5-methoxytryptamine, not a peptide. The formula and identifiers below apply only when the batch matches neutral melatonin rather than a salt, solvate or formulation [1].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | N-acetyl-5-methoxytryptamine, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)acetamide |
| Material category | Neurohormone |
| Sequence | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide |
| Molecular formula | C13H16N2O2 |
| Average molecular mass | 232.278 g/mol |
| CAS Registry Number | 73-31-4 |
| PubChem CID | CID 896 |
| Structural features | Indoleamine derived from tryptophan. It is an N-acetylated and O-methylated derivative of serotonin. |
| Appearance | White to off-white crystalline powder |
| Solubility | Slightly soluble in water. Soluble in ethanol, DMSO, and other organic solvents. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
A neurohormone primarily released by the pineal gland that regulates sleep-wake cycles. Widely used as a dietary supplement for sleep.
Research background and published evidence
Published research
Melatonin is used in MT1/MT2 receptor-binding and signaling studies, circadian cell-system research and analytical-method development [2,3].
Current scientific understanding
Receptor and structural publications describe defined research systems and do not establish safety, efficacy or suitability for this catalogue batch. Regulatory classification and permitted supply vary by jurisdiction.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Catalogue melatonin material, subject to exact-form batch confirmation | Exact neutral melatonin reference standard |
| Structural distinction | Salt, solvate, formulation and nominal content remain batch-specific | Defined N-acetyl-5-methoxytryptamine without formulation excipients |
| Analytical implication | Confirm identity, form and analyte content against a matching standard and CoA | Reference formula, mass, CAS and CID apply only to the matching neutral molecule |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Melatonin, CID 896.
- [2] Reppert et al. Molecular characterization of a melatonin receptor. Neuron (1994).
- [3] Stauch et al. Structural basis of ligand recognition at the MT1 melatonin receptor. Nature (2019).
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.
