HCG
Price range: $41.00 through $75.00
HCG is supplied as a catalogued research material in 5000 IU and 10000 IU; IU denotes biological activity, not mass.
“HCG” does not establish whether the material is urinary-derived hCG, recombinant choriogonadotropin alfa or another preparation. These materials can differ in glycosylation, impurities, potency and controls. IU states biological activity rather than molecular or protein mass; source, identity and specific activity require a signed specification and matching batch evidence [1–3].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | HCG, hCG, Choriogonadotropin |
| Material category | Glycoprotein Hormone |
| Sequence | Alpha chain (CGA) + Beta chain (CGB) |
| Average molecular mass | 36700 g/mol |
| CAS Registry Number | 9002-61-3 |
| Structural features | Heterodimeric glycoprotein composed of a 92-amino acid alpha subunit and a 145-amino acid beta subunit. The subunits are non-covalently linked. Both subunits are heavily glycosylated. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in aqueous solutions. Reconstitute with bacteriostatic water or sterile water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Human Chorionic Gonadotropin (HCG) is a hormone produced during pregnancy. It is a heterodimer consisting of an alpha subunit (common to LH, FSH, TSH) and a unique beta subunit. The molecular weight is an approximation and varies due to the high degree of glycosylation. The CAS 9002-61-3 typically refers to HCG purified from the urine of pregnant women.
Research background and published evidence
Published research
A fully characterized hCG preparation can support immunoassay, receptor-binding, glycoprotein-characterization and potency-method research. Those workflows require source-specific reference standards, subunit identity, glycan characterization and a validated activity assay.
Current scientific understanding
Evidence and authorization for separately manufactured urinary or recombinant prescription medicines do not verify this catalogue vial. They do not establish its source, identity, purity, potency, viral safety, sterility, efficacy, dosage, administration or interchangeability [1–3].
Authorised hCG products are prescription medicines, FDA states they are not approved for weight loss, and hCG is covered by current anti-doping restrictions [2–4].
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Catalogue HCG with unresolved urinary/recombinant source and glycoform | Defined recombinant choriogonadotropin alfa reference or authorised finished medicine |
| Structural distinction | Source, expression system, glycan distribution, excipients and specific activity are not publicly resolved | Manufacturing source, glycoprotein controls, potency and formulation are specified |
| Analytical implication | Requires subunit identity, glycan profile, purity/aggregates, source-impurity controls and validated IU potency | Reference values apply only to the matching source, construct, glycoform and potency method |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Choriogonadotropin alfa: recombinant glycoprotein reference description.
- [2] European Medicines Agency. Ovitrelle: authorised prescription choriogonadotropin alfa medicine.
- [3] U.S. FDA. Questions and answers on HCG products for weight loss.
- [4] World Anti-Doping Agency. 2026 Prohibited List.
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.
