MT-2
❄️Lyophilized powder (not reconstituted)
$32.99
MT-2 is supplied as a catalogued research material in 10 mg.
MT-2/Melanotan II is a defined cyclic lactam peptide rather than a linear melanocortin analogue. The formula and identifiers apply only when the batch confirms the exact ring connectivity, stereochemistry, termini and non-salt form [1,2].
Chemical properties and registry information
| Property | Value |
|---|---|
| Name and synonyms | MT-2, MT-II, Melanotan-2 |
| Material category | Melanocortin Receptor Agonist |
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 |
| Molecular formula | C50H69N15O9 |
| Average molecular mass | 1024.18 g/mol |
| CAS Registry Number | 121062-08-6 |
| PubChem CID | CID 92432 |
| Structural features | Cyclic heptapeptide analog of α-MSH with an Ac-Nle N-terminus, a D-Phe at position 4, and a lactam bridge between Asp-2 and Lys-7. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Soluble in bacteriostatic water or sterile water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.
Potent, non-selective agonist for melanocortin receptors MC1, MC3, MC4, and MC5. Investigated for tanning (skin pigmentation) and erectile dysfunction.
Research background and published evidence
Published research
Melanotan II was developed as a constrained melanocortin analogue and is used in receptor-binding, signaling and structure–activity research [2].
Current scientific understanding
Receptor and structure–activity findings do not establish safety, efficacy or suitability for this catalogue batch. Melanotan II is not an authorized medicinal product.
Technical comparison
| Aspect | This catalogue material | Comparator |
|---|---|---|
| Identity | Cyclic heptapeptide Melanotan II, subject to exact-form batch confirmation | Linear Melanotan I/afamelanotide-type peptide |
| Structural distinction | Short Asp–Lys lactam ring with Nle, D-Phe, N-acetyl and C-amide features | Longer linear melanocortin analogue without the MT-2 lactam ring |
| Analytical implication | Confirm cyclic connectivity, D-Phe stereochemistry, termini, intact mass and salt form | Linear-peptide mass and sequence identifiers do not establish MT-2 identity |
Quality and testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory handling and storage
Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and legal status
| Research-use notice | This material is supplied exclusively for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements. |
Sources and references
- [1] PubChem. Melanotan II, CID 92432.
- [2] Al-Obeidi et al. Design of a potent cyclic α-MSH analogue. Journal of Medicinal Chemistry (1989).
Frequently Asked Questions
Do the CAS number and PubChem CID apply to every batch form?
Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.
What does an analytical purity result mean?
It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.
How should the material be stored and handled?
Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.
